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Writer's pictureThe Resuscitation Coach

Adenosine

Updated: Jan 22, 2022



ADENOSINE:

Naturally occurring organic compound and an Endogenous Purine Nucleoside. When given as an anti-arrhythmic, it slows AV nodal conduction and interrupts reentrant AV pathways, thus often terminating supraventricular tachycardias as a "chemical cardioverter.".

Adenosine is a Class Five Anti-arrhythmic.


WHEN TO GIVE:

• The first drug for most forms of stable narrow-complex SVT and is effective in terminating those due to reentry, involving AV node or sinus node.

•We may consider for unstable narrow-complex reentry tachycardia while preparing for cardioversion ⚡️

•Stable wide, regular tachycardias prior to Amiodarone. May give when unstable while preparing to cardioversion ⚡️


ADULT ADMINISTRATION:

•Short half-life; must be given quickly so it gets to the heart while still effective

•Initial bolus of 6 mg given over 1 to 3 seconds followed by NS flush of 20 mL 💦

• A second dose of 12 mg can be given in 1 to 2 minutes if needed.


PEDIATRIC ADMINISTRATION:

•Short half-life; must be given quickly so it gets to the heart while still effective

•Initial bolus of 0.1mg/kg mg given over 1 to 3 seconds followed by NS flush of 5-10 ml💦

• A second dose of 0.2mg/kg mg can be given in 1 to 2 minutes if needed.


SIDE EFFECTS:

•Chest Pain, Chest Tightness

•Nausea & Vomiting

•Light headedness, Dizziness, Headache

•Hypotension

•Bradycardia, Asystole- be ready to start CPR.


Disclaimer: This video is for educational purposes only and is not intended as medical advice. While we strive for 100% accuracy, errors may occur, and medications or protocols may change over time.

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